National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Diagnostic and therapeutic approaches to infections caused by free-living amoebae pathogenic to humans
Štofaniková, Petra ; Nohýnková, Eva (advisor) ; Stejskal, František (referee)
Naegleria fowleri, Balamuthia mandrillaris and Acanthamoeba spp. are free-living amoebae which rarely cause human infections. N. fowleri induces primary amoebic meningoencephalitis mostly among children and young adults. B. mandrillaris is the causative agent of Balamuthia amoebic encephalitis and skin lesions with complicated healing. Amoebas of the genus Acanthamoeba are the ethiologic agent of focal granulomatous encephalitis. Its clinical presentation is almost the same as in Balamuthia encephalitis, but it occures mainly in immunocompromised patients. It can also affect lungs and skin. The infection of central nervous system usually has a fatal end. In immunocompetent people Acanthamoeba keratitis can occur. Unproper use of contact lenses or trauma of the cornea represents increased risk level. Without correct treatment Acanthamoeba keratitis can lead to sight loss. In all infections caused by free-living amoebae, early diagnosis and initialisation of effective therapy are essential for better prognosis. This thesis discusses contemporary diagnostic and therapeutic approaches to these infections.

Interested in being notified about new results for this query?
Subscribe to the RSS feed.